AUSTIN -- It's fitting that First Lady Michelle Obama delivered the first keynote of the South by Southwest music festival.

Sitting on a panel with Obama was Queen Latifah, Missy Elliot, Sophia Bush and Diane Warren. Obama issued a call to action for the Let Girls Learn program, aimed at helping the 62 million girls around the world who are unable to attend school.

"Today there are 62 million young girls who are not in school around the world. Adolescent girls who aren't getting an education because there are cultural norms that keep them down," Obama said.

The women on stage talked about their lives -- the trials and tribulations they each faced.

"I've been told, so many times 'what you do won't work, you don't fit the mold, you don't look like, the way that other artist look,'" Elliot said. "I wasn't the correct size."

Obama adds that growing up, a lot of people told her she wasn't going to make it.

"Growing up as a Black girl on the Southside of Chicago where the expectations were limited," Obama said. "As I was trying to make my way and do things in school and apply to good colleges, there were always people around telling me what I couldn't do."

Elliot and Obama said people telling them they can't fueled their passion to pursue their dreams. Now, they're asking others to help them fuel opportunity for girls around the world.

On the same day of the address, a song commissioned by Obama, written by Warren and starting Missy Elliot along with other artists was released called "This Is For My Girls".

Obama announced during the keynote that the song is available for purchase on iTunes and 100 percent of the proceeds from the sale of the song will go to the Let Girls Learn initiative.

"We can have an impact on these girls and they don't even know we're doing it," Obama said. "You know, they don't know that here in the United States at South by Southwest, sitting on this stage are a group of women that care so deeply."

The speakers didn't focus solely on the initiative during the hour long talk. They also took questions from the audience and talked about which music albums inspired them.

Obama talked about continuing her work post-White House and the ladies broke into song, singing a line from the Boyz II Men song "It's So Hard To Say Goodbye To Yesterday."

The last question to the first lady, which received resounding applause from the crowd, was if she will make a presidential run.

Obama said no, saying having one parent as president is enough for her two young daughters. But she added she will continue her work on the initiatives she started while in the White House.

For more information on the Let Girls Learn initiative, go here.